Tumour cell activity markers in epithelial ovarian cancer: are biochemical and cytometric indices complementary?
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Skeletal Muscle Depletion and Markers for Cancer Cachexia Are Strong Prognostic Factors in Epithelial Ovarian Cancer
OBJECTIVE Tumor cachexia is an important prognostic parameter in epithelial ovarian cancer (EOC). Tumor cachexia is characterized by metabolic and inflammatory disturbances. These conditions might be reflected by body composition measurements (BCMs) ascertained by pre-operative computed tomography (CT). Thus, we aimed to identify the prognostically most relevant BCMs assessed by pre-operative C...
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BACKGROUND Factors contributing to chronic inflammation appear to be associated with increased risk of ovarian cancer. The purpose of this study was to assess the association between circulating levels of inflammation mediators and subsequent risk of ovarian cancer. METHODS We conducted a case-control study of 230 cases and 432 individually matched controls nested within three prospective coh...
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Introduction: Adequate screening methods are not available for early stage ovarian cancer detection. We hypothesised that correlating the levels of phase I and phase II biotransformation enzymes involved in estrogen metabolism and correlating it with cell proliferation and apoptosis evasion would provide key hallmark traits for ovarian malignancy. The aim of the study was to evaluate the expres...
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background ovarian cancer is the most common fatal gynecologic malignancy in women. the brca2 gene has a role in regulation of cell cycle during proliferation, differentiation and dna repair. changes in the methylation of brca2 may be an effective mechanism for ovarian cancer. objectives the aim of the present study was to evaluate the association between ovarian cancer and methylation status o...
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ژورنال
عنوان ژورنال: British Journal of Cancer
سال: 1990
ISSN: 0007-0920,1532-1827
DOI: 10.1038/bjc.1990.168